Table 1 Main andrological parameters across age groups

LAURENTINO, Sandra, et al. A germ cell‐specific ageing pattern in otherwise healthy men. Aging cell, 2020, 19. Jg., Nr. 10, S. e13242.

Publication: https://doi.org/10.1111/acel.13242

Description

Normal ranges are indicated for each parameter. Results are shown as mean (SD) for each age group and Spearmans rank correlations with age as ρ (p‐value).

Disclaimer

The publication A germ cell‐specific ageing pattern in otherwise healthy men by Sandra Laurentino, Jann‐Frederik Cremers, Bernhard Horsthemke, Frank Tüttelmann, Karen Czeloth, Michael Zitzmann, Eva Pohl, Sven Rahmann, Christopher Schröder, Sven Berres, Klaus Redmann, Claudia Krallmann, Stefan Schlatt, Sabine Kliesch, Jörg Gromoll is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Share — copy and redistribute the material in any medium or format. Adapt — remix, transform, and build upon the material for any purpose, even commercially.

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Pararmeters	Group_1N = 3418–25 years	Group_2N = 3626–35 years	Group_3N = 283645 years	Group_4N = 3946–55 years	Group_5N = 3656–65 years	Group_6N = 24>66 years	CorrelationWithAge
DHT (0.5–2.0 nmol/l)	0.9 (0.2)	0.8 (0.2)	0.8 (0.2)	0.8 (0.3)	0.8 (0.3)	1.0 (0.4)	−0.004 (0.95)
Ejaculate volume (≥1.5 ml)	4.2 (1.7)	4.6 (2.3)	3.7 (1.8)	3.2 (1.5)	2.9 (1.5)	2.0 (1.2)	−0.41 (3.86 × 10^−9
Free testosterone (>250 pmol/l)	494.4 (128.5)	501.5 (103.8)	435.8 (138.7)	369.0 (111.3)	361.2 (84.9)	361.3 (117.4)	−0.47 (6.89 × 10^−12)
FSH (2–10 U/l)	3.0 (1.9)	3.4 (1.5)	4.0 (2.0)	4.1 (2.4)	5.2 (5.9)	6.1 (3.0)	0.36 (2.08 × 10−7)
LH (1–7 U/l)	3.0 (0.9)	3.2 (1.1)	3.5 (1.5)	3.0 (1.1)	2.8 (1.2)	4.0 (1.7)	0.02 (0.81)
Normal morphology (≥4%)	4.9 (1.7)	4.7 (1.8)	4.6 (2.0)	5.2 (2.1)	4.4 (2.2)	5.1 (2.1)	0.01 (0.85)
Oestradiol (<250 pmol/l)	89.0 (31.3)	86.8 (26.9)	85.6 (34.8)	78.1 (28.8)	88.5 (32.2)	98.1 (33.4746)	0.01 (0.87)
pH (≥7.2)	8.1 (0.3)	8.1 (0.3)	8.3 (0.3)	8.2 (0.3)	8.4 (0.5)	8.2 (0.3)	0.19 (0.009)
Progressive motility (≥32%)	55.2 (15.1)	57.9 (12.5)	47.8 (16.4)	49.8 (16.2)	43.4 (18.7)	35.6 (21.1)	−0.39 (1.68 × 10^−8)
Prolactin (<500 mU/l)	297.0 (165.0)	303.0 (204.4)	225.5 (97.2)	189.4 (118.2)	165.3 (92.6)	199.4 (56.9)	−0.38 (3.43 × 101−8)
Prostate‐specific antigen (<4 µg/l)	0.5 (0.2)	0.6 (0.3)	0.7 (0.5)	0.9 (0.8)	1.5 (1.3)	1.9 (1.7)	0.45 (2.70 × 10^-11)
SHBG (11–71 nmol/l)	38.2 (12.8)	36.6 (12.8)	37.2 (11.9)	39.7 (13.1)	47.3 (17.7)	58.8 (19.3)	0.32 (3.56 × 10^−6)
Sperm concentration (≥15 million/ml)	39.5 (37.3)	47.6 (37.8)	34.5 (30.7)	53.5 (45.1)	52.7 (50.1)	62.9 (43.8)	0.08 (0.29)
Testicular volume (>15 cm3)	43.2 (13.4)	41.5 (13.8)	42.3 (15.7)	39.1 (12.5)	42.7 (12.9)	39.6 (13.4)	−0.05 (0.51)
Total sperm count (≥39 million)	142.3 (116.2)	206.5 (179.5)	118.7 (86.0)	165.4 (160.3)	139.1 (140.5)	122.3 (120.8)	−0.14 (0.06)
Total testosterone (>12 nmol/l)	23.9 (7.3)	23.8 (6.7)	21.2 (6.8)	19.4 (6.2)	20.8 (6.2)	24.1 (9.3)	−0.12 (0.09)
Vitality (>58%)	71.2 (11.5)	70.5 (11.4)	66.0 (14.2)	69.3 (11.4)	60.6 (15.8)	59.3 (15.9)	−0.31 (1.99 × 10^−5)

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