A novel cross-species inhibitor to study the function of CatSper Ca 2+ channels in sperm
A. Rennhack, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover SJ, Kaupp UB, Strünker T., 03.05.2018
RENNHACK, Andreas, et al. A novel cross‐species inhibitor to study the function of CatSper Ca2+ channels in sperm. British journal of pharmacology, 2018, 175. Jg., Nr. 15, S. 3144-3161.
Publication: https://doi.org/10.1111/bph.14355
Disclaimer
The publication A novel cross-species inhibitor to study the function of CatSper Ca 2+ channels in sperm by A. Rennhack, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover SJ, Kaupp UB, Strünker T. is not published under an open access license.
Therefore, only content curated by the MFGA team can be shown.
For abstract, images and tables please follow the link to the original publication.
Curation by the MFGA team
Relevant data sets presented in the publication have been identified. If possible, annotations (title, general information,
conditions, processed tissue types and processed cell types) have been added based on information from the publication.
Data set 1: Synthesis of RU1968
Other: Functional Study
Conditions
Human phenotype ontology |
Participants |
Comment |
HP:other: Other |
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Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000019: sperm |
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Human |
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Data set 2: RU1968F1 is a potent cross‐species inhibitor of CatSper channels
Other: Functional Study
Species
Species |
Human |
Sea Urchin |
Mouse |
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000019: sperm |
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Human Fig 3. Mouse Fig 4. Sea urchin Fig 5. Human and mouse Fig 6. |
Sperm cells of human, mouse and sea urchin |
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Data set 3: RU1968F1 inhibits human but not mouse Slo3 channels
Other: Functional Study
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000019: sperm |
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from human and mouse |
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Data set 4: RU19681F1 suppresses progesterone‐evoked motility responses in human sperm
Other: Functional Study
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000019: sperm |
|
|
Human |
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