DNA Demethylation Dynamics in the Human Prenatal Germline
Sofia Gkountela, Kelvin X. Zhang, Tiasha A. Shafiq, Wen-Wie Liao, Joseph Hargan-Calvopiña, Pao-Yang Chen, Amander T. Clark, 04.06.2015
GKOUNTELA, Sofia, et al. DNA demethylation dynamics in the human prenatal germline. Cell, 2015, 161. Jg., Nr. 6, S. 1425-1436.
Publication: https://doi.org/10.1016/j.cell.2015.05.012
Repository: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63392;https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63393
Disclaimer
The publication DNA Demethylation Dynamics in the Human Prenatal Germline by Sofia Gkountela, Kelvin X. Zhang, Tiasha A. Shafiq, Wen-Wie Liao, Joseph Hargan-Calvopiña, Pao-Yang Chen, Amander T. Clark is not published under an open access license.
Therefore, only content curated by the MFGA team can be shown.
For abstract, images and tables please follow the link to the original publication.
Curation by the MFGA team
Relevant data sets presented in the publication have been identified. If possible, annotations (title, general information,
conditions, processed tissue types and processed cell types) have been added based on information from the publication.
Data set 1: Transcriptional landmarks of human prenatal germline development
Transcriptome: Bulk RNA-Sequencing
Tissue Types
BRENDA tissue ontology |
Maturity |
Description |
Species |
Replicates |
BTO_0000975: ovary |
Prenatal |
|
Human |
9 |
BTO_0001363: testis |
Prenatal |
|
Human |
6 |
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000670: primordial germ cell |
Primordial |
|
Human |
7 |
|
|
|
Human advanced germline cells (hAGCs) |
Human |
8 |
|
CL_0002322: embryonic stem cell |
Embryonic |
|
Human |
4 |
|
Data set 2: DNA methylation in the human germline using developmental landmarks as guides
Methylome: Whole Genome Bisulfite Sequencing
Tissue Types
BRENDA tissue ontology |
Maturity |
Description |
Species |
Replicates |
BTO_0000975: ovary |
Prenatal |
|
Human |
4 |
BTO_0001363: testis |
Prenatal |
|
Human |
2 |
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000670: primordial germ cell |
Primordial |
Human primordial germ cells (hPGCs) |
Human |
3 |
|
|
|
Advanced germline cells (hAGCs) |
Human |
3 |
|
CL_0002322: embryonic stem cell |
Embryonic |
|
Human |
5 |
|
|
Embryonic |
Human inner cell mass (hICM) |
Human |
1 |
|