The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells
Fan Guo, Liying Yan, Hongshan Guo, Lin Li, Boqiang Hu, Yangyu Zhao, Jun Yong, Yuqiong Hu, Xiaoye Wang, Yuan Wie, Wie Wang, Rong Li, Jie Yan, Xu Zhi, Yan Zhang, Hongyan Jin, Wenxin Zhang, YuHou…Jie Qiao, 04.06.2015
GUO, Fan, et al. The transcriptome and DNA methylome landscapes of human primordial germ cells. Cell, 2015, 161. Jg., Nr. 6, S. 1437-1452.
Publication: https://doi.org/10.1016/j.cell.2015.05.015
Repository: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63818
Disclaimer
The publication The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells by Fan Guo, Liying Yan, Hongshan Guo, Lin Li, Boqiang Hu, Yangyu Zhao, Jun Yong, Yuqiong Hu, Xiaoye Wang, Yuan Wie, Wie Wang, Rong Li, Jie Yan, Xu Zhi, Yan Zhang, Hongyan Jin, Wenxin Zhang, YuHou…Jie Qiao is not published under an open access license.
Therefore, only content curated by the MFGA team can be shown.
For abstract, images and tables please follow the link to the original publication.
Curation by the MFGA team
Relevant data sets presented in the publication have been identified. If possible, annotations (title, general information,
conditions, processed tissue types and processed cell types) have been added based on information from the publication.
Data set 1: Transcriptional Profiles of Human PGCs
Transcriptome: Single-cell RNA-Sequencing
Tissue Types
BRENDA tissue ontology |
Maturity |
Description |
Species |
Replicates |
BTO_0000534: gonad |
Embryonic |
|
Human |
|
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000670: primordial germ cell |
Primordial |
|
Human |
15 |
233 |
CL_0002371: somatic cell |
Embryonic |
Gonadal |
Human |
13 |
86 |
Data set 2: Dynamic Methylome Analysis of Human PGCs Revealed a Global DNA Hypomethylation Pattern
Methylome: Whole Genome Bisulfite Sequencing
Tissue Types
BRENDA tissue ontology |
Maturity |
Description |
Species |
Replicates |
BTO_0000142: brain |
Embryonic |
5 week post-implantation embryo |
Human |
1.0 |
BTO_0000562: heart |
Embryonic |
5 week post-implantation embryo |
Human |
1.0 |
BTO_0000759: liver |
Embryonic |
5 week post-implantation embryo |
Human |
1.0 |
BTO_0000379: embryo |
|
|
Human |
|
Cell Types
Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
CL_0000670: primordial germ cell |
Primordial |
|
Human |
|
10.0 |
CL_0002371: somatic cell |
Embryonic |
Gonadal |
Human |
11.0 |
|
CL_0000352: epiblast cell |
Embryonic |
E6.5 post-implantation |
Mouse |
1.0 |
2.0 |
|
Embryonic |
Inner cell mass (ICM) |
Human |
1.0 |
1.0 |
CL_0000670: primordial germ cell |
Primordial |
|
Mouse |
1.0 |
8.0 |
CL_0002322: embryonic stem cell |
Embryonic |
Human embryonic stem cells |
Human |
1.0 |
6.0 |