Supplementary table S5
LUKASSEN, Soeren, et al. Characterization of germ cell differentiation in the male mouse through single-cell RNA sequencing. Scientific reports, 2018, 8. Jg., Nr. 1, S. 6521-6521.
Publication: https://doi.org/10.1038/s41598-018-24725-0
Description
Differential gene expression revealed 21 potential marker genes for spermatogonia, 24 for Sertoli cells, and 20 for Leydig cells. These genes were significantly (p < 0.01) upregulated (log2 fold change > 7) in the respective population (Supplementary data Table S5).
Disclaimer
The publication Characterization of germ cell differentiation in the male mouse through single-cell RNA sequencing by S. Lukassen, E. Bosch , A. B. Ekici & A. Winterpacht is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Permits to share, copy and redistribute the material in any medium or format and to adapt, remix, transform, and build upon the material for any purpose, even commercially.
Curation by the MFGA team
Pie chart of selected column
Table
| ARTIFACTID | GENE | sertoliAverage | sertoliLog2FoldChange | sertoliP-Value | spermatogoniaAverage | spermatogoniaLog2FoldChange | spermatogoniaP-Value | leydigAverage | leydigLog2FoldChange | leydigP-Value |
|---|---|---|---|---|---|---|---|---|---|---|
| ENSMUSG00000025789 | St8sia2 | 1.99 | 12.43 | 1.62E-03 | 0 | 6.43 | 1.00E+00 | 0 | 6.7 | 1 |
| ENSMUSG00000108077 | 6330415B21Rik | 1.71 | 12.24 | 0.00695 | 0 | 6.62 | 1 | 0 | 6.89 | 1 |
| ENSMUSG00000042429 | Adora1 | 7.12 | 11.54 | 0.000131 | 0 | 4.47E+00 | 1 | 0 | 4.75 | 1 |
| ENSMUSG00000031853 | Map3k21 | 1.42 | 11.01 | 0.000847 | 0 | 6.62 | 1 | 0 | 6.89 | 1 |
| ENSMUSG00000031342 | Gpm6b | 11.11 | 10.84 | 0.00013 | 0 | 3.67E+00 | 1 | 0.37 | 4.97 | 0.303 |
| ENSMUSG00000037035 | Inhbb | 3.42 | 10.81 | 0.000283 | 0 | 5.34 | 1 | 0 | 5.61 | 1 |
| ENSMUSG00000040102 | Klhl42 | 1.14 | 10.75 | 0.00562 | 0 | 6.84 | 1 | 0 | 7.12 | 1 |
| ENSMUSG00000044400 | Sowahd | 1.71 | 10.65 | 0.00191 | 0 | 6.26E+00 | 1 | 0 | 6.53 | 1 |
| ENSMUSG00000044667 | Plppr4 | 1.71 | 10.65 | 0.0028 | 0 | 6.26 | 1 | 0 | 6.53 | 1 |
| ENSMUSG00000043753 | Dmrta1 | 2.28 | 10.6 | 0.000621 | 0 | 5.84 | 1 | 0 | 6.12 | 1 |
| ENSMUSG00000024867 | Pip5k1b | 4.56 | 10.52 | 0.000131 | 0 | 4.84E+00 | 1 | 0 | 5.12 | 1 |
| ENSMUSG00000072966 | Gprasp2 | 3.13 | 10.43 | 0.000307 | 0 | 5.34 | 1 | 0 | 5.61 | 1 |
| ENSMUSG00000112287 | RP24-528H20.6 | 1.99 | 10.43 | 0.00113 | 0 | 5.97E+00 | 1 | 0 | 6.24 | 1 |
| ENSMUSG00000032796 | Lama1 | 1.42 | 10.43 | 0.00127 | 0 | 6.43 | 1 | 0 | 6.7 | 1 |
| ENSMUSG00000024176 | Sox8 | 1.42 | 10.43 | 0.00216 | 0 | 6.43 | 1 | 0 | 6.7 | 1 |
| ENSMUSG00000026872 | Zeb2 | 2.56 | 10.43 | 0.000442 | 0 | 5.62E+00 | 1 | 0.73 | 7.7 | 0.0784 |
| ENSMUSG00000039910 | Cited2 | 4.56 | 10.35 | 0.000152 | 0 | 4.78 | 1 | 1.47 | 7.63 | 0.0466 |
| ENSMUSG00000022425 | Enpp2 | 3.42 | 10.32 | 0.000771 | 0 | 5.18 | 1 | 0 | 5.45 | 1 |
| ENSMUSG00000045763 | Basp1 | 4.56 | 10.19 | 0.000131 | 0 | 4.72E+00 | 1 | 0 | 5 | 1 |
| ENSMUSG00000002602 | Axl | 5.41 | 10.16 | 0.000394 | 0 | 4.47 | 1 | 0 | 4.75 | 1 |
| ENSMUSG00000016239 | Lonrf3 | 1.71 | 7.53 | 0.0148 | 3.7 | 8.98E+00 | 0.00231 | 0 | 4.7 | 1 |
| ENSMUSG00000042105 | Inpp5f | 0.57 | 7.43 | 0.0583 | 1.42 | 8.84 | 0.0157 | 0 | 5.89 | 1 |
| ENSMUSG00000040147 | Maob | 0 | 7.43 | 1 | 0 | 7.43 | 1 | 1.1 | 11.7 | 0.00264 |
| ENSMUSG00000110982 | RP24-374N16.7 | 0 | 7.43 | 1 | 0 | 7.43E+00 | 1 | 1.1 | 11.7 | 0.00602 |
| ENSMUSG00000039114 | Nrn1 | 0 | 7.43 | 1 | 0 | 7.43 | 1 | 1.1 | 11.7 | 0.00771 |
| ENSMUSG00000032717 | Mdfi | 0 | 7.43 | 1 | 0 | 7.43 | 1 | 1.1 | 11.7 | 0.00602 |
| ENSMUSG00000049307 | Fut4 | 0 | 7.43 | 1 | 0 | 7.43E+00 | 1 | 1.1 | 11.7 | 0.00241 |
| ENSMUSG00000060882 | Kcnd2 | 0 | 7.43 | 1 | 0 | 7.43 | 1 | 1.1 | 11.7 | 0.00264 |
| ENSMUSG00000035226 | Rims4 | 0 | 7.11 | 1 | 0 | 7.10E+00 | 1 | 1.47 | 12.02 | 0.00217 |
| ENSMUSG00000041936 | Agrn | 0.28 | 6.97 | 0.144 | 1.71 | 9.65 | 0.0206 | 0 | 6.12 | 1 |
| ENSMUSG00000049047 | Armcx3 | 0 | 6.84 | 1 | 0 | 6.84 | 1 | 1.83 | 12.29 | 0.00128 |
| ENSMUSG00000025666 | Tmem47 | 0 | 6.84 | 1 | 0 | 6.84E+00 | 1 | 1.47 | 11.02 | 0.00315 |
| ENSMUSG00000097124 | A530020G20Rik | 0 | 6.84 | 1 | 0 | 6.84 | 1 | 1.83 | 12.29 | 0.00155 |
| ENSMUSG00000038679 | Trps1 | 0 | 6.84 | 1 | 0 | 6.84 | 1 | 1.47 | 11.02 | 0.00347 |
| ENSMUSG00000045659 | Plekha7 | 0.28 | 6.73 | 0.13 | 1.99 | 9.62E+00 | 0.0358 | 0 | 5.89 | 1 |
| ENSMUSG00000035258 | Abi3bp | 0 | 6.62 | 1 | 0 | 6.62 | 1 | 1.83 | 11.29 | 0.00378 |
| ENSMUSG00000035948 | Acss3 | 0 | 6.62 | 1 | 0 | 6.62E+00 | 1 | 1.83 | 11.29 | 0.00229 |
| ENSMUSG00000009248 | Ascl2 | 0 | 6.62 | 1 | 1.14 | 10.16 | 0.0325 | 0.37 | 8.12 | 0.108 |
| ENSMUSG00000000058 | Cav2 | 0 | 6.62 | 1 | 0 | 6.62 | 1 | 1.83 | 11.29 | 0.00811 |
| ENSMUSG00000036098 | Myrf | 0 | 6.43 | 1 | 1.14 | 9.75E+00 | 0.0111 | 0 | 6.7 | 1 |
| ENSMUSG00000074207 | Adh1 | 0 | 6.26 | 1 | 0 | 6.26 | 1 | 2.56 | 11.7 | 0.000736 |
| ENSMUSG00000039601 | Rcan2 | 0 | 6.26 | 1 | 0 | 6.26 | 1 | 2.2 | 10.92 | 0.00595 |
| ENSMUSG00000002870 | Mcm2 | 0.28 | 6.18 | 2.01E-01 | 3.7 | 10.43 | 1.70E-03 | 0 | 5.38 | 1.00E+00 |
| ENSMUSG00000018604 | Tbx3 | 0 | 6.11 | 1.00E+00 | 0 | 6.1 | 1.00E+00 | 2.56 | 11.12 | 4.03E-03 |
| ENSMUSG00000028040 | Efna4 | 0 | 5.97E+00 | 1.00E+00 | 1.14 | 8.94 | 4.54E-02 | 0 | 6.24 | 1.00E+00 |
| ENSMUSG00000034832 | Tet3 | 0 | 5.84 | 1.00E+00 | 1.42 | 9.2 | 2.67E-02 | 0.73 | 7.97 | 6.77E-02 |
| ENSMUSG00000002028 | Kmt2a | 0.57 | 5.69 | 1.63E-01 | 4.55 | 8.81 | 1.73E-03 | 0.37 | 5.34 | 3.63E-01 |
| ENSMUSG00000032291 | Crabp1 | 0.28 | 5.62E+00 | 2.56E-01 | 4.26 | 9.62 | 1.73E-03 | 0 | 4.84 | 1.00E+00 |
| ENSMUSG00000036109 | Mbnl3 | 0 | 5.62 | 1.00E+00 | 1.42 | 8.84 | 2.41E-02 | 0 | 5.89 | 1.00E+00 |
| ENSMUSG00000019979 | Apaf1 | 0 | 5.62E+00 | 1.00E+00 | 1.42 | 8.84 | 2.06E-02 | 0 | 5.89 | 1.00E+00 |
| ENSMUSG00000053559 | Smagp | 0 | 5.52 | 1.00E+00 | 2.27 | 9.79 | 9.91E-03 | 0.37 | 6.89 | 1.78E-01 |
| ENSMUSG00000060177 | Klk1b22 | 0 | 5.43 | 1.00E+00 | 0 | 5.43 | 1.00E+00 | 4.76 | 11.92 | 1.62E-03 |
| ENSMUSG00000108981 | Gm15262 | 0 | 5.18E+00 | 1.00E+00 | 2.27 | 9.14 | 6.96E-03 | 0 | 5.45 | 1.00E+00 |
| ENSMUSG00000038521 | C1s1 | 0 | 4.97 | 1.00E+00 | 0 | 4.97 | 1.00E+00 | 5.5 | 10.89 | 7.35E-04 |
| ENSMUSG00000055612 | Cdca7 | 0 | 4.9 | 1.00E+00 | 2.84 | 9.18 | 1.73E-03 | 0 | 5.18 | 1.00E+00 |
| ENSMUSG00000044150 | A830080D01Rik | 0 | 4.62E+00 | 1.00E+00 | 2.84 | 8.71 | 8.93E-03 | 0 | 4.89 | 1.00E+00 |
| ENSMUSG00000041020 | Map7d2 | 0 | 4.47 | 1.00E+00 | 3.13 | 8.69 | 6.98E-03 | 0 | 4.75 | 1.00E+00 |
| ENSMUSG00000029177 | Cenpa | 0 | 3.38E+00 | 1.00E+00 | 12.79 | 10.56 | 9.03E-04 | 0 | 3.66 | 1.00E+00 |
| ENSMUSG00000029848 | Stra8 | 0 | 3.3 | 1.00E+00 | 8.81 | 9.14 | 3.18E-02 | 0 | 3.57 | 1.00E+00 |
| ENSMUSG00000005268 | Prlr | 0 | 2.55 | 1.00E+00 | 0 | 2.54 | 1.00E+00 | 31.88 | 11.21 | 2.59E-04 |