Table S1: List of highly differentially expressed genes in bulk RNA-seq data from GnRH-treated versus vehicle-treated LβT2 cells.
RUF-ZAMOJSKI, Frederique, et al. Regulatory architecture of the LβT2 gonadotrope cell underlying the response to gonadotropin-releasing hormone. Frontiers in endocrinology, 2018, 9. Jg., S. 34.
Publication: https://www.frontiersin.org/articles/10.3389/fendo.2018.00034/full
Description
Disclaimer
The publication Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone by Frederique Ruf-Zamojski, Miguel Fribourg, Yongchao Ge, Venugopalan Nair, Hanna Pincas, Elena Zaslavsky, German Nudelman, Stephanie J. Tuminello, Hideo Watanabe, Judith L. Turgeon and Stuart C. Sealfon is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Granted rights: share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material for any purpose, even commercially.
Curation by the MFGA team
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Table
| ARTIFACTID | GENE | PVALUE | Log2foldchange | Basemean | _T | Padj | Maxmean |
|---|---|---|---|---|---|---|---|
| ENSMUSG00000071341.4 | Egr4 | 1.620000e-08 | 8.98898127032776 | -0.623727101067135 | 19.9777395753217 | 9.82E-06 | 3.87278540534896 |
| ENSMUSG00000038418.7 | Egr1 | 1.890000e-13 | 8.88574122413744 | 6.06323109478824 | 77.0042149788345 | 3.25E-09 | 10.5056735755867 |
| ENSMUSG00000037868.15 | Egr2 | 9.030000e-11 | 8.4696796650979 | 3.64462027726033 | 37.0519404769239 | 2.11E-07 | 7.87940679076142 |
| ENSMUSG00000033730.3 | Egr3 | 5.930000e-06 | 8.17339954989252 | -1.13032636574279 | 9.6533755810508 | 0.000871313898584 | 2.94904773429596 |
| ENSMUSG00000003545.2 | Fosb | 9.590000e-11 | 8.07858192272878 | 4.5347558211357 | 36.7498924812839 | 2.11E-07 | 8.58029816797528 |
| ENSMUSG00000023034.6 | Nr4a1 | 5.690000e-08 | 7.35572401519852 | 5.24503951353348 | 17.0892857750456 | 2.33E-05 | 8.93134197556827 |
| ENSMUSG00000028341.9 | Nr4a3 | 9.790000e-11 | 6.94017270846858 | 5.60742386683995 | 36.5188240141138 | 2.11E-07 | 9.07419216157401 |
| ENSMUSG00000026826.13 | Nr4a2 | 1.310000e-08 | 6.89148137536202 | -0.083092431568295 | 20.3646618515819 | 8.66E-06 | 3.36562625555833 |
| ENSMUSG00000085609.1 | 1700016P03Rik | 3.480000e-09 | 6.79524562862187 | 0.76736099957278 | 23.8611784599952 | 2.99E-06 | 4.16334914409145 |
| ENSMUSG00000021250.13 | Fos | 3.960000e-12 | 6.60764659762575 | 5.66070189393927 | 53.3390021597969 | 3.40E-08 | 8.96402350986945 |
| ENSMUSG00000100816.1 | Gm28321 | 4.290000e-09 | 5.89376985537382 | 1.28083678901197 | 23.1793699619803 | 3.21E-06 | 4.23684007463565 |
| ENSMUSG00000045903.8 | Npas4 | 3.050000e-08 | 5.84836190193854 | 4.26412235112791 | 18.3071428379868 | 1.50E-05 | 7.19027768955514 |
| ENSMUSG00000084390.1 | Gm15425 | 2.400000e-05 | 5.60769892915607 | 0.43845784690424 | 7.97303810218004 | 0.002505337126436 | 3.24476497142441 |
| ENSMUSG00000026628.13 | Atf3 | 3.200000e-09 | 5.60411531983301 | 5.49091224038245 | 23.9699761352873 | 2.90E-06 | 8.29771373235265 |
| ENSMUSG00000044786.5 | Zfp36 | 4.870000e-11 | 5.1864550112904 | 5.89425741145476 | 39.3456341306246 | 2.09E-07 | 8.48594053774744 |
| ENSMUSG00000049649.8 | Gpr3 | 4.360000e-07 | 4.75178059014849 | -0.349466471043307 | 13.1637400605897 | 0.000109662463504 | 2.02653649245716 |
| ENSMUSG00000034765.6 | Dusp5 | 1.150000e-08 | 4.70290735153607 | 1.7633981046833 | 20.4522838492933 | 7.92E-06 | 4.10420577676105 |
| ENSMUSG00000020423.6 | Btg2 | 1.450000e-09 | 4.61641530578627 | 8.52296927766029 | 26.1973452920332 | 2.03E-06 | 10.833345547622 |
| ENSMUSG00000108413.1 | BC026762 | 3.590000e-07 | 4.55648516562686 | -0.242704855206308 | 13.4638037474116 | 9.66E-05 | 2.0161873476814 |
| ENSMUSG00000105954.1 | Gm42793 | 2.280000e-07 | 4.54171147972431 | 1.86300067790099 | 14.2300600736898 | 7.02E-05 | 4.12628207327404 |
| ENSMUSG00000052684.4 | Jun | 7.030000e-11 | 4.47922230427416 | 5.0639551425431 | 37.4987252671244 | 2.11E-07 | 7.30312048514138 |
| ENSMUSG00000086683.1 | Gm12867 | 4.420000e-07 | 4.40673547662502 | -0.568425391941143 | 13.1091310131951 | 0.000109662463504 | 1.64800757939954 |
| ENSMUSG00000024042.6 | Sik1 | 2.080000e-08 | 4.36815884912338 | 5.78550634925216 | 18.9995953155761 | 1.19E-05 | 7.97380379055009 |
| ENSMUSG00000102376.1 | Gm37975 | 6.130000e-06 | 4.23604315856559 | 1.24472401114294 | 9.42607131519351 | 0.000885958606527 | 3.37149075907921 |
| ENSMUSG00000053560.4 | Ier2 | 1.401469e-04 | 4.22727232631955 | 0.065561053676919 | 6.22313471563488 | 0.009203159963039 | 2.18124329571117 |
| ENSMUSG00000090582.1 | Gm17024 | 3.210000e-08 | 4.19498747263067 | 2.88902972015051 | 18.0084826279571 | 1.54E-05 | 4.98884141938432 |
| ENSMUSG00000100009.6 | Gm7967 | 3.960000e-09 | 4.18091096096364 | 4.25951065522721 | 23.1532578836679 | 3.21E-06 | 6.34653830989581 |
| ENSMUSG00000102329.1 | Gm10851 | 2.840000e-06 | 4.09725780484143 | 0.459747381809671 | 10.3766289083359 | 0.000484520056178 | 2.50506497585114 |
| ENSMUSG00000047407.17 | Tgif1 | 6.810000e-10 | 4.08780648628024 | 2.53298866785462 | 28.5463796209773 | 1.17E-06 | 4.57171357619705 |
| ENSMUSG00000052837.5 | Junb | 8.676966e-04 | 3.98973875185521 | -0.453064410165323 | 4.75721072623315 | 0.034637400727017 | 1.57705950934513 |
| ENSMUSG00000056749.7 | Nfil3 | 1.130000e-07 | 3.95274174805789 | 3.96624465480673 | 15.441339669586 | 4.12E-05 | 5.94133515700443 |
| ENSMUSG00000097472.1 | Gm26586 | 2.200000e-08 | 3.87211039251259 | 1.4056286567462 | 18.798617755832 | 1.20E-05 | 3.34784967565902 |
| ENSMUSG00000087502.1 | Gm16091 | 2.540000e-09 | 3.83471004752163 | 2.68679157034351 | 24.3430210521256 | 2.57E-06 | 4.60615491122524 |
| ENSMUSG00000085178.1 | Kdm6bos | 2.770000e-07 | 3.74478124901252 | 1.43383486641859 | 13.8108103032856 | 7.93E-05 | 3.30354399652983 |
| ENSMUSG00000101122.1 | Gm17971 | 1.270000e-05 | 3.71674002450467 | 0.53905051332223 | 8.54228235678052 | 0.001583902597449 | 2.38962662092466 |
| ENSMUSG00000029135.10 | Fosl2 | 3.160000e-11 | 3.68783280348231 | 6.31318466112812 | 40.9695911113799 | 1.81E-07 | 8.15654577931516 |
| ENSMUSG00000042622.13 | Maff | 2.640000e-07 | 3.65833034843839 | 2.37157710312586 | 13.8770733147845 | 7.84E-05 | 4.20576100323275 |
| ENSMUSG00000000078.6 | Klf6 | 1.530000e-09 | 3.64707323208045 | 7.02359972442374 | 25.8212746848977 | 2.03E-06 | 8.84293169543852 |
| ENSMUSG00000074804.3 | AU015228 | 2.690000e-08 | 3.55703731697913 | 1.18162253502985 | 18.2977169129042 | 1.36E-05 | 2.95426066637887 |
| ENSMUSG00000044317.7 | Gpr4 | 2.150000e-05 | 3.51144781776595 | -0.719569575952426 | 7.95815968394833 | 0.002331787490898 | 1.03796623642871 |
| ENSMUSG00000025981.13 | Coq10b | 1.490000e-07 | 3.4193789791406 | 6.51766826939486 | 14.8538807761771 | 5.01E-05 | 8.21936287264676 |
| ENSMUSG00000003032.8 | Klf4 | 2.230000e-08 | 3.30940124334851 | 3.1148678924908 | 18.6667600162834 | 1.20E-05 | 4.77272672387037 |
| ENSMUSG00000024190.6 | Dusp1 | 1.330000e-09 | 3.284394754752 | 5.10940897311358 | 26.1561588360624 | 2.03E-06 | 6.75210335510829 |
| ENSMUSG00000024912.5 | Fosl1 | 1.600000e-06 | 3.28304482330433 | 1.80749920500197 | 11.0640026765563 | 0.00029982305453 | 3.45618657283602 |
| ENSMUSG00000103046.1 | Gm37309 | 1.820000e-09 | 3.25769688395414 | 3.07671042879299 | 25.1999788299186 | 2.10E-06 | 4.70665183830966 |
| ENSMUSG00000097889.1 | Gm26541 | 6.840000e-07 | 3.24363496627794 | 1.52390841961292 | 12.2933457425354 | 0.000159120009115 | 3.14509079126562 |
| ENSMUSG00000026360.9 | Rgs2 | 1.560000e-08 | 3.24295152728657 | 5.16248080688573 | 19.4793391990622 | 9.82E-06 | 6.78006730245338 |
| ENSMUSG00000054364.4 | Rhob | 4.770000e-09 | 3.23925056535716 | 4.60978245669345 | 22.4510773364393 | 3.42E-06 | 6.23046961028421 |
| ENSMUSG00000065147.1 | Snora31 | 5.970000e-07 | 3.22871769657195 | 0.96482239301577 | 12.5002784736855 | 0.000142686505183 | 2.57247424547141 |
| ENSMUSG00000096934.1 | Gm26658 | 1.670000e-06 | 3.21307350133278 | 0.657662555830363 | 10.9986870050287 | 0.000309106070544 | 2.2591915118023 |
| ENSMUSG00000039568.6 | Ubald1 | 7.750000e-08 | 3.19354947673774 | 4.49476816130707 | 16.0405793294289 | 2.96E-05 | 6.09324625869059 |
| ENSMUSG00000081490.1 | Gm11830 | 9.240000e-07 | 3.18015136608972 | 1.42948427063066 | 11.8360726412591 | 0.000203874298095 | 3.02200489629014 |
| ENSMUSG00000001225.12 | Slc26a3 | 1.100000e-06 | 3.13369388392777 | -0.103009199981758 | 11.5722100192567 | 0.000228773503826 | 1.45587442962604 |
| ENSMUSG00000034855.13 | Cxcl10 | 1.400000e-05 | 3.13051080031473 | 0.429049137018962 | 8.38603537795081 | 0.001681790029635 | 1.99001262202983 |
| ENSMUSG00000035356.16 | Nfkbiz | 3.070000e-10 | 3.1205600550452 | 4.46774121670907 | 31.1016802550808 | 5.87E-07 | 6.02703843013342 |
| ENSMUSG00000019850.11 | Tnfaip3 | 6.030000e-08 | 3.10973097685426 | 3.91780061415637 | 16.5210510155642 | 2.41E-05 | 5.47512698291987 |
| ENSMUSG00000081265.1 | Gm11282 | 1.330000e-06 | 3.10759877290379 | 0.891469377223583 | 11.3070475070794 | 0.000268472955215 | 2.43660149746942 |
| ENSMUSG00000040435.10 | Ppp1r15a | 5.480000e-05 | 3.01948047764002 | 5.71264654779618 | 6.98814689105742 | 0.004556194124336 | 7.23233659891815 |
| ENSMUSG00000036820.11 | Amdhd2 | 4.996407e-04 | -2.92268514843749 | 0.590443584643725 | -5.1049940635436 | 0.023313764020287 | 2.05369131801952 |
| ENSMUSG00000040528.15 | Milr1 | 4.230000e-06 | 2.9117991831747 | 0.517000409904083 | 9.75151812483981 | 0.000673274296805 | 1.96361181919868 |
| ENSMUSG00000077167.1 | Gm24119 | 1.710000e-07 | 2.88803950883034 | 0.900433118717492 | 14.5151640535954 | 5.56E-05 | 2.34891854948892 |
| ENSMUSG00000007617.17 | Homer1 | 4.250000e-07 | 2.87050187349704 | 6.70973426124266 | 12.9836791484294 | 0.000109662463504 | 8.13865955075774 |
| ENSMUSG00000036931.14 | Nfkbid | 6.320000e-07 | 2.86576037435704 | 2.72282686474142 | 12.3623745412141 | 0.000148905875618 | 4.15515037012624 |
| ENSMUSG00000006720.16 | Zfp184 | 4.300000e-08 | 2.85021542986642 | 5.27140399098653 | 17.1621058164307 | 1.95E-05 | 6.69390270153913 |
| ENSMUSG00000038205.12 | Prkab2 | 2.260000e-09 | 2.84492451364973 | 5.21698084993383 | 24.4416513892359 | 2.43E-06 | 6.63808437124762 |
| ENSMUSG00000105434.1 | Gm43359 | 1.860000e-05 | 2.7734125343763 | 3.22940341158569 | 8.04522456629464 | 0.00205934487086 | 4.62570007331412 |
| ENSMUSG00000106458.1 | Gm42633 | 5.730000e-05 | 2.72265502106085 | 0.791510062442699 | 6.91808458470919 | 0.004669783683659 | 2.16345961416171 |
| ENSMUSG00000023467.16 | Tulp2 | 3.720000e-05 | 2.7187180509305 | 0.756740781379428 | 7.33132249933376 | 0.003505992237992 | 2.12999151967119 |
| ENSMUSG00000031397.11 | Tktl1 | 1.470000e-05 | 2.71149427057924 | 1.11693571200781 | 8.28617903454858 | 0.001709884500255 | 2.46008681207131 |
| ENSMUSG00000085148.1 | Mir22hg | 2.850000e-09 | 2.67208000957018 | 3.90316379963156 | 23.7240459070907 | 2.73E-06 | 5.23694476243866 |
| ENSMUSG00000086624.1 | Gm16130 | 6.050000e-06 | 2.66273363728831 | 1.04270390927914 | 9.28567979931178 | 0.000882723570192 | 2.36962425862613 |
| ENSMUSG00000079364.3 | Gm3558 | 3.730000e-06 | 2.62832556019018 | 1.0642874956523 | 9.87270523876742 | 0.000610647517016 | 2.38050871757813 |
| ENSMUSG00000042507.14 | Elmsan1 | 1.830000e-09 | 2.60044463546853 | 6.28640096210608 | 24.9932075950324 | 2.10E-06 | 7.58554139582022 |
| ENSMUSG00000091275.1 | Gm3248 | 5.100000e-06 | 2.57159210983271 | 1.13301110861193 | 9.47972876032456 | 0.000762949164552 | 2.41264119134581 |
| ENSMUSG00000032578.7 | Cish | 7.450000e-06 | 2.56477938815386 | 1.45756087225897 | 9.03013827052228 | 0.001042133249924 | 2.74916203682828 |
| ENSMUSG00000022518.15 | 4930562C15Rik | 1.250000e-07 | 2.54132728801998 | 2.038872807615 | 15.0156092556651 | 4.49E-05 | 3.31340993047464 |
| ENSMUSG00000003752.9 | Itpkc | 2.970000e-05 | 2.5412121080614 | 4.902731588464 | 7.53698899054056 | 0.00290267593579 | 6.17817320314425 |
| ENSMUSG00000019960.7 | Dusp6 | 9.530000e-05 | 2.53150480915806 | 0.183287265416145 | 6.43542767231094 | 0.006832478815401 | 1.4637428108217 |
| ENSMUSG00000102258.1 | Gm38257 | 1.500000e-05 | 2.52917280721017 | 1.60216243414034 | 8.24266507632243 | 0.001734664629027 | 2.86790287074799 |
| ENSMUSG00000043953.12 | Ccrl2 | 1.270000e-05 | 2.52331710830614 | 0.127523387698071 | 8.42240584856842 | 0.001583902597449 | 1.37949213719809 |
| ENSMUSG00000047180.8 | Neurl3 | 4.080000e-08 | 2.49016052028102 | 2.50120376397566 | 17.1947846745677 | 1.90E-05 | 3.74415180629832 |
| ENSMUSG00000003541.6 | Ier3 | 4.480000e-06 | 2.48422621057059 | 2.42994286452313 | 9.62558459209565 | 0.00070733264071 | 3.67046121388421 |
| ENSMUSG00000106691.1 | 2700029L08Rik | 1.460000e-05 | 2.4601615403941 | 0.488464281899217 | 8.26845360849181 | 0.001709884500255 | 1.71663612382206 |
| ENSMUSG00000097487.7 | Ptges3l | 1.310000e-07 | 2.43937378792148 | 1.44299224018338 | 14.9110182507571 | 4.61E-05 | 2.66094673992469 |
| ENSMUSG00000037428.14 | Vgf | 2.646912e-04 | 2.39564042392793 | 1.84639742139094 | 5.5580969222864 | 0.014596190729192 | 3.05275054676958 |
| ENSMUSG00000020692.14 | Nle1 | 1.789681e-04 | -2.38319448616442 | 0.323982033570624 | -5.8778167288188 | 0.01095781498218 | 1.50569679863285 |
| ENSMUSG00000034168.6 | Irf2bpl | 5.240000e-08 | 2.34051487426909 | 5.66771162732301 | 16.6509299412588 | 2.25E-05 | 6.83444203093052 |
| ENSMUSG00000001627.11 | Ifrd1 | 1.550000e-06 | 2.29377172739172 | 6.78382937417807 | 10.9791527060366 | 0.000295527833854 | 7.92666211420211 |
| ENSMUSG00000027196.11 | Alkbh3os1 | 1.460000e-07 | 2.29197814106838 | 2.84305672431919 | 14.6925984208408 | 5.01E-05 | 3.98684846558839 |
| ENSMUSG00000055413.12 | H2-Q5 | 2.940000e-05 | 2.22424638921762 | 1.02881722980349 | 7.50984313778301 | 0.002893669201188 | 2.14890126746423 |
| ENSMUSG00000020718.12 | Polg2 | 4.780000e-08 | 2.21185031899431 | 3.87388844430668 | 16.8083374215558 | 2.11E-05 | 4.98194210343683 |
| ENSMUSG00000097296.1 | Gm26532 | 1.280000e-05 | 2.20312026906202 | 0.825806884089513 | 8.37658215749883 | 0.001583902597449 | 1.92588314439051 |
| ENSMUSG00000087552.2 | Gm15819 | 4.690000e-05 | 2.18773937355315 | 0.210926024985621 | 7.05210004701968 | 0.004155783175276 | 1.30082769647425 |
| ENSMUSG00000054556.6 | Gm4876 | 4.560000e-06 | 2.18494545496115 | 0.562468341581605 | 9.5625278525529 | 0.000708186757134 | 1.65436142927103 |
| ENSMUSG00000028195.4 | Cyr61 | 3.495373e-04 | 2.184029864556 | 1.29229044509139 | 5.31678396787352 | 0.018005357185025 | 2.39174541750309 |
| ENSMUSG00000028214.13 | Gem | 9.810000e-08 | 2.17511732693346 | 6.03306232563438 | 15.3952443202793 | 3.67E-05 | 7.11647420717839 |
| ENSMUSG00000027829.15 | Ccnl1 | 1.530000e-06 | 2.16589797789091 | 7.38768958717256 | 10.9736977373171 | 0.000295527833854 | 8.46848037957006 |
| ENSMUSG00000049516.8 | Spty2d1 | 4.600000e-07 | 2.16413076118669 | 8.37963149155455 | 12.7391952743454 | 0.000111496309225 | 9.46108828775574 |
| ENSMUSG00000060477.14 | Irak2 | 5.510000e-08 | 2.15243496556878 | 4.3910545869136 | 16.5067000977472 | 2.31E-05 | 5.46242708203778 |
| ENSMUSG00000047963.7 | Stbd1 | 1.660000e-08 | 2.14075316688617 | 3.61174345149678 | 19.0850705164195 | 9.82E-06 | 4.68232322780274 |
| ENSMUSG00000037411.10 | Serpine1 | 9.020000e-06 | 2.13697876853236 | 2.94604687277261 | 8.75622242572519 | 0.0012080348594 | 4.0144203691691 |
| ENSMUSG00000081756.1 | Gm12291 | 5.740000e-05 | 2.10740878613607 | 0.67318811332777 | 6.8511407037088 | 0.004669783683659 | 1.72676648344662 |
| ENSMUSG00000038268.4 | Ovca2 | 1.960000e-07 | 2.10006740576889 | 4.42395162086939 | 14.1357458795052 | 6.24E-05 | 5.47294316310079 |
| ENSMUSG00000005718.7 | Tfap4 | 5.636269e-04 | -2.09513558836081 | 0.941041043346431 | -4.94177337113183 | 0.02518753240486 | 1.99512141188281 |
| ENSMUSG00000108053.1 | Gm43890 | 8.010000e-06 | 2.09256716898581 | 2.29382756143797 | 8.88619914909772 | 0.001101004164063 | 3.33770094748139 |
| ENSMUSG00000017418.13 | Arl5b | 1.080000e-05 | 2.06464832037698 | 8.32900660567077 | 8.54255986232338 | 0.001400354765893 | 9.36028541716375 |
| ENSMUSG00000092090.2 | Gm3294 | 8.450000e-07 | 2.04812824933218 | 1.99016007077224 | 11.7968399921829 | 0.000188805045915 | 3.00742081969822 |
| ENSMUSG00000087006.3 | Gm13889 | 2.371262e-04 | 2.04325448992792 | 0.682438096706458 | 5.61171608981905 | 0.013384401706593 | 1.6996815106444 |
| ENSMUSG00000027660.16 | Skil | 2.740000e-07 | 2.03671948942023 | 7.2482585356923 | 13.5529880552978 | 7.93E-05 | 8.26478640802294 |
| ENSMUSG00000034640.9 | Tiparp | 1.420000e-05 | 2.02766528737575 | 7.52062845633894 | 8.23822506870492 | 0.001701632893248 | 8.53244464000824 |
| ENSMUSG00000020275.9 | Rel | 1.410000e-06 | 2.02349908879704 | 7.17901477245443 | 11.0648366901418 | 0.000281850587124 | 8.18840058831621 |
| ENSMUSG00000029551.13 | Psmg3 | 1.261588e-03 | -2.02185755011536 | 0.981577657500241 | -4.3505661704234 | 0.046182175359177 | 1.99347539939986 |