Table S5: List of differentially expressed genes in GEM Drop-seq data from GnRH-treated versus vehicle-treated LβT2 cells
RUF-ZAMOJSKI, Frederique, et al. Regulatory architecture of the LβT2 gonadotrope cell underlying the response to gonadotropin-releasing hormone. Frontiers in endocrinology, 2018, 9. Jg., S. 34.
Publication: https://www.frontiersin.org/articles/10.3389/fendo.2018.00034/full
Description
Disclaimer
The publication Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone by Frederique Ruf-Zamojski, Miguel Fribourg, Yongchao Ge, Venugopalan Nair, Hanna Pincas, Elena Zaslavsky, German Nudelman, Stephanie J. Tuminello, Hideo Watanabe, Judith L. Turgeon and Stuart C. Sealfon is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Granted rights: share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material for any purpose, even commercially.
Curation by the MFGA team
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Table
| ARTIFACTID | GENE | PVALUE | Mean_veh | Mean_gnrh | Log2fc | P_adj |
|---|---|---|---|---|---|---|
| ENSMUSG00000071341 | Egr4 | 6.240000e-144 | 0.001446929714309 | 4.41088848988922 | -11.1589548056885 | 5.50E-140 |
| ENSMUSG00000045903 | Npas4 | 1.750000e-82 | 0.00048230990477 | 0.648630425786954 | -9.39430982867204 | 3.85E-79 |
| ENSMUSG00000037868 | Egr2 | 4.330000e-112 | 0.003376169333389 | 1.74026484867316 | -8.81744531808635 | 1.53E-108 |
| ENSMUSG00000023034 | Nr4a1 | 1.020000e-151 | 0.039549412191123 | 15.9239525510214 | -8.63585348594136 | 1.80E-147 |
| ENSMUSG00000003545 | Fosb | 1.770000e-106 | 0.004823099047698 | 1.80880699156906 | -8.41372946063055 | 5.20E-103 |
| ENSMUSG00000021250 | Fos | 1.330000e-133 | 0.038102482476814 | 9.53995752115094 | -7.94985164626113 | 7.80E-130 |
| ENSMUSG00000024912 | Fosl1 | 1.110000e-43 | 0.00048230990477 | 0.146156039998614 | -7.24826829346571 | 1.15E-40 |
| ENSMUSG00000038418 | Egr1 | 1.070000e-116 | 0.126847504954456 | 14.215942828417 | -6.80281559051916 | 4.71E-113 |
| ENSMUSG00000026628 | Atf3 | 3.530000e-75 | 0.013022367428784 | 1.26752565722936 | -6.55295423537911 | 5.65E-72 |
| ENSMUSG00000028341 | Nr4a3 | 5.280000e-49 | 0.003858479238158 | 0.278704448687013 | -6.0072101151643 | 6.20E-46 |
| ENSMUSG00000052837 | Junb | 3.250000e-93 | 0.195817821336537 | 11.251999134514 | -5.84100976019473 | 8.17E-90 |
| ENSMUSG00000053560 | Ier2 | 3.820000e-80 | 0.076687274858397 | 3.24516807431406 | -5.39430982867205 | 7.48E-77 |
| ENSMUSG00000020423 | Btg2 | 1.210000e-77 | 0.505943090103514 | 16.8885824150123 | -5.05956645612547 | 2.13E-74 |
| ENSMUSG00000023868 | Pde10a | 7.630000e-70 | 0.109484348382743 | 3.34898926134756 | -4.92877351408472 | 1.12E-66 |
| ENSMUSG00000044786 | Zfp36 | 4.590000e-64 | 0.057394878667606 | 1.6263639347432 | -4.81292721822669 | 6.22E-61 |
| ENSMUSG00000034765 | Dusp5 | 4.860000e-34 | 0.006270028762007 | 0.154723807860602 | -4.52282456919473 | 4.28E-31 |
| ENSMUSG00000024042 | Sik1 | 8.100000e-45 | 0.016398536762173 | 0.362366181927599 | -4.42596302994214 | 8.92E-42 |
| ENSMUSG00000052684 | Jun | 1.670000e-56 | 0.449030521340679 | 7.93375304020065 | -4.14162967373857 | 2.10E-53 |
| ENSMUSG00000040435 | Ppp1r15a | 2.570000e-37 | 0.154339169526334 | 1.59461279501937 | -3.36495324775083 | 2.38E-34 |
| ENSMUSG00000020024 | Cep83 | 5.500000e-38 | 0.16350305771696 | 1.62686792108802 | -3.31087374003371 | 5.38E-35 |
| ENSMUSG00000055148 | Klf2 | 1.470000e-21 | 0.02266856552418 | 0.207642374066997 | -3.16842842125572 | 9.97E-19 |
| ENSMUSG00000034936 | Arl4d | 1.380000e-22 | 0.020739325905101 | 0.172867316274223 | -3.03022608662223 | 1.06E-19 |
| ENSMUSG00000015605 | Srf | 1.880000e-27 | 0.221380246289336 | 1.40712987474528 | -2.665502757893 | 1.57E-24 |
| ENSMUSG00000024190 | Dusp1 | 5.930000e-22 | 0.058359498477145 | 0.353798414065611 | -2.59003649206708 | 4.35E-19 |
| ENSMUSG00000056749 | Nfil3 | 8.720000e-17 | 0.02411549523849 | 0.141116176550386 | -2.52539392880686 | 4.39E-14 |
| ENSMUSG00000087006 | Gm13889 | 3.740000e-23 | 0.302890620195431 | 1.67625858288066 | -2.46648289456101 | 2.99E-20 |
| ENSMUSG00000040752 | Myh6 | 2.910000e-20 | 0.095979671049189 | 0.530193634753594 | -2.45982648180842 | 1.83E-17 |
| ENSMUSG00000022602 | Arc | 4.480000e-17 | 0.044372511238821 | 0.229817773239201 | -2.36028449450747 | 2.32E-14 |
| ENSMUSG00000025981 | Coq10b | 8.530000e-22 | 0.341957722481784 | 1.69087418688052 | -2.30424473660521 | 6.01E-19 |
| ENSMUSG00000037887 | Dusp8 | 9.910000e-20 | 0.11768361676383 | 0.575552405787647 | -2.28536469976934 | 6.02E-17 |
| ENSMUSG00000029135 | Fosl2 | 3.620000e-19 | 0.099355840382578 | 0.483322904685073 | -2.27679658866662 | 2.13E-16 |
| ENSMUSG00000027368 | Dusp2 | 3.950000e-14 | 0.050160230096059 | 0.237377568411543 | -2.23179048225315 | 1.70E-11 |
| ENSMUSG00000032515 | Csrnp1 | 2.010000e-11 | 0.02411549523849 | 0.107349091447258 | -2.13243459498708 | 6.94E-09 |
| ENSMUSG00000054364 | Rhob | 7.400000e-18 | 0.207393259051012 | 0.903647516267295 | -2.12081306638759 | 4.07E-15 |
| ENSMUSG00000038205 | Prkab2 | 1.920000e-15 | 0.059324118286685 | 0.258544994894101 | -2.11482118936443 | 9.38E-13 |
| ENSMUSG00000042507 | Elmsan1 | 1.530000e-14 | 0.053054089524677 | 0.225281896135795 | -2.07633200626493 | 6.94E-12 |
| ENSMUSG00000097296 | Gm26532 | 5.880000e-14 | 0.045337131048361 | 0.19201879737749 | -2.07096617026223 | 2.41E-11 |
| ENSMUSG00000079364 | Gm3558 | 7.910000e-11 | 0.025562424952799 | 0.102813214343853 | -1.98798554789941 | 2.58E-08 |
| ENSMUSG00000038930 | Rccd1 | 4.870000e-14 | 0.075722655048858 | 0.293320052686874 | -1.94696427558082 | 2.04E-11 |
| ENSMUSG00000060477 | Irak2 | 1.470000e-10 | 0.032797073524346 | 0.122468681791942 | -1.88560583134215 | 4.72E-08 |
| ENSMUSG00000008136 | Fhl2 | 2.420000e-13 | 0.099838150287347 | 0.36438212730689 | -1.86279911949954 | 9.25E-11 |
| ENSMUSG00000028214 | Gem | 8.550000e-14 | 0.138905252573701 | 0.506002290202099 | -1.86144705412304 | 3.42E-11 |
| ENSMUSG00000020893 | Per1 | 1.540000e-14 | 0.195817821336537 | 0.708604800820868 | -1.85291457952771 | 6.94E-12 |
| ENSMUSG00000003032 | Klf4 | 1.380000e-09 | 0.033761693333886 | 0.122972668136765 | -1.85028377005532 | 3.99E-07 |
| ENSMUSG00000029860 | Zyx | 8.000000e-12 | 0.075240345144088 | 0.259048981238923 | -1.77720082373638 | 2.88E-09 |
| ENSMUSG00000029074 | Ttll10 | 1.910000e-09 | 0.032314763619576 | 0.110373009516195 | -1.75728982283175 | 5.33E-07 |
| ENSMUSG00000049892 | Rasd1 | 3.640000e-10 | 0.049195610286519 | 0.16681948013635 | -1.75193185472114 | 1.15E-07 |
| ENSMUSG00000036931 | Nfkbid | 3.630000e-09 | 0.033761693333886 | 0.113900913929955 | -1.74019431834366 | 9.68E-07 |
| ENSMUSG00000087445 | Gm14286 | 7.220000e-11 | 0.255624249527991 | 0.07710991075789 | 1.72238855955182 | 2.40E-08 |
| ENSMUSG00000079737 | 3110001I22Rik | 6.950000e-10 | 0.04726637066744 | 0.156235766895071 | -1.71480710060842 | 2.11E-07 |
| ENSMUSG00000014773 | Dll1 | 9.140000e-10 | 0.049195610286519 | 0.162283603032944 | -1.71228277806814 | 2.73E-07 |
| ENSMUSG00000044471 | Lncpint | 4.900000e-10 | 0.057394878667606 | 0.184962988549971 | -1.68006431100592 | 1.52E-07 |
| ENSMUSG00000037428 | Vgf | 1.180000e-08 | 0.081028064001326 | 0.258544994894101 | -1.66813806346912 | 3.01E-06 |
| ENSMUSG00000034168 | Irf2bpl | 9.210000e-12 | 0.685362374677878 | 2.0461845599806 | -1.57730651286234 | 3.24E-09 |
| ENSMUSG00000000078 | Klf6 | 4.810000e-09 | 0.075240345144088 | 0.223265950756504 | -1.56318806801591 | 1.25E-06 |
| ENSMUSG00000035356 | Nfkbiz | 1.510000e-08 | 0.060288738096224 | 0.175387247998337 | -1.53319625326716 | 3.80E-06 |
| ENSMUSG00000003348 | Mob3a | 1.860000e-08 | 0.051607159810368 | 0.150187930757197 | -1.53250712259206 | 4.49E-06 |
| ENSMUSG00000000134 | Tfe3 | 2.930000e-11 | 1.15754377144751 | 3.3454613569338 | -1.53072349884918 | 9.93E-09 |
| ENSMUSG00000029641 | Rasl11a | 2.030000e-07 | 0.085851163049023 | 0.233849663997783 | -1.44066407928857 | 4.21E-05 |
| ENSMUSG00000025578 | Cbx8 | 1.600000e-09 | 0.242601882099207 | 0.653166302890359 | -1.42707579130921 | 4.54E-07 |
| ENSMUSG00000042622 | Maff | 1.710000e-07 | 0.092121191811031 | 0.235361623032251 | -1.34879516941968 | 3.62E-05 |
| ENSMUSG00000008348 | Ubc | 3.210000e-09 | 5.31216129113452 | 13.4256922397348 | -1.33751753792781 | 8.76E-07 |
| ENSMUSG00000062825 | Actg1 | 3.230000e-09 | 7.82547820488991 | 19.7688643756747 | -1.33689578375564 | 8.76E-07 |
| ENSMUSG00000042745 | Id1 | 1.560000e-08 | 0.882144815823954 | 2.19939640880673 | -1.31753095590283 | 3.83E-06 |
| ENSMUSG00000097554 | Gm26825 | 1.080000e-07 | 0.154821479431104 | 0.383533608410157 | -1.30612325993613 | 2.36E-05 |
| ENSMUSG00000038152 | 5033430I15Rik | 1.670000e-06 | 0.057877188572375 | 0.142628135584855 | -1.29427683278752 | 0.000302387448101 |
| ENSMUSG00000028967 | Errfi1 | 8.430000e-08 | 0.237778783051509 | 0.57605639213247 | -1.27489705575114 | 1.88E-05 |
| ENSMUSG00000017418 | Arl5b | 9.680000e-08 | 0.223791795813185 | 0.541281334339696 | -1.27242698903886 | 2.13E-05 |
| ENSMUSG00000026204 | Ptprn | 6.020000e-08 | 0.441795872769132 | 1.06693909198988 | -1.27110190095471 | 1.40E-05 |
| ENSMUSG00000038393 | Txnip | 8.020000e-08 | 1.12667593754224 | 0.471731218754148 | 1.25514383056621 | 1.81E-05 |
| ENSMUSG00000035529 | Prdm4 | 3.050000e-06 | 0.067523386667771 | 0.161275630343299 | -1.25027108528094 | 0.000531696254735 |
| ENSMUSG00000034640 | Tiparp | 2.750000e-07 | 0.266717377337696 | 0.621919149511345 | -1.21994611098028 | 5.56E-05 |
| ENSMUSG00000022010 | Tsc22d1 | 6.410000e-08 | 7.29059652050021 | 16.9505727354255 | -1.21714145327506 | 1.47E-05 |
| ENSMUSG00000005103 | Wdr1 | 1.220000e-07 | 0.673786936963403 | 1.5578217918473 | -1.20856890910684 | 2.61E-05 |
| ENSMUSG00000039568 | Ubald1 | 5.320000e-07 | 0.177007735050515 | 0.408228939306475 | -1.20338909871769 | 9.97E-05 |
| ENSMUSG00000002983 | Relb | 2.560000e-06 | 0.103696629525506 | 0.238889527446011 | -1.20028915161227 | 0.000455271521535 |
| ENSMUSG00000025498 | Irf7 | 4.390000e-06 | 0.084886543239484 | 0.19554670179125 | -1.19941374546062 | 0.000750657496512 |
| ENSMUSG00000000486 | Sept1 | 2.790000e-06 | 0.231991064194271 | 0.101301255309384 | 1.19128490292074 | 0.000491855493169 |
| ENSMUSG00000101493 | 2810405F17Rik | 3.110000e-05 | 0.105143559239815 | 0.045862757378876 | 1.18783215298673 | 0.004727355121762 |
| ENSMUSG00000027829 | Ccnl1 | 4.050000e-07 | 0.56285565886635 | 1.26298978012596 | -1.16531467251135 | 7.92E-05 |
| ENSMUSG00000039989 | Cbx4 | 5.140000e-07 | 0.401764150673239 | 0.89911163916389 | -1.16119773602923 | 9.72E-05 |
| ENSMUSG00000049516 | Spty2d1 | 7.830000e-07 | 0.464946748198082 | 1.02863612978335 | -1.14477496927979 | 0.000145181388947 |
| ENSMUSG00000024423 | Impact | 8.890000e-06 | 0.150480690288176 | 0.321039301652129 | -1.09078671738968 | 0.001436014909402 |
| ENSMUSG00000100096 | Gm28760 | 5.770000e-06 | 0.536810924008781 | 0.25300114510105 | 1.08372597697708 | 0.000976649534948 |
| ENSMUSG00000049606 | Zfp644 | 2.460000e-06 | 0.89179101391935 | 1.87079731198226 | -1.06845299500849 | 0.000441242225052 |
| ENSMUSG00000003541 | Ier3 | 1.352519e-04 | 0.100320460192117 | 0.210666292135934 | -1.0668402521759 | 0.01804485863783 |
| ENSMUSG00000070803 | Cited4 | 3.260000e-06 | 4.08082410425723 | 8.42866763081664 | -1.04632857061726 | 0.000562242683273 |
| ENSMUSG00000035621 | Midn | 7.660000e-06 | 0.320253776767143 | 0.660222111717879 | -1.04263439039063 | 0.001272350173016 |
| ENSMUSG00000026360 | Rgs2 | 1.840000e-05 | 0.298067521147733 | 0.607807531856307 | -1.02680731209819 | 0.002873448860996 |
| ENSMUSG00000022519 | Srl | 1.317508e-04 | 0.068488006477311 | 0.139604217515918 | -1.02246268650255 | 0.017711940030756 |
| ENSMUSG00000037573 | Tob1 | 8.450000e-06 | 0.823785317346809 | 1.66517088329456 | -1.01489082527634 | 0.001391290877766 |
| ENSMUSG00000068154 | Insm1 | 8.610000e-06 | 1.39725179411809 | 2.80821191335269 | -1.0067895090786 | 0.001403258262049 |
| ENSMUSG00000074629 | 4930518I15Rik | 1.704437e-04 | 0.142281421907089 | 0.070558088275193 | 1.00650906267273 | 0.022400629637995 |
| ENSMUSG00000027313 | Chac1 | 3.550000e-05 | 0.222827176003645 | 0.448043860547477 | -1.00618609315095 | 0.005341741250147 |
| ENSMUSG00000073388 | A330017A19Rik | 1.176385e-04 | 0.176043115240975 | 0.087693623999169 | 1.00109577589429 | 0.016059940620353 |