Table 2: DEPs involved in the functional pathways implicated in male infertility.
AGARWAL, Ashok; PANNER SELVAM, Manesh Kumar; BASKARAN, Saradha. Proteomic analyses of human sperm cells: understanding the role of proteins and molecular pathways affecting male reproductive health. International journal of molecular sciences, 2020, 21. Jg., Nr. 5, S. 1621.
Publication: https://doi.org/10.3390/ijms21051621
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The publication Proteomic Analyses of Human Sperm Cells: Understanding the Role of Proteins and Molecular Pathways Affecting Male Reproductive Health by Ashok Agarwal, Manesh Kumar Panner Selvam and Saradha Baskaran is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Granted rights: share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material for any purpose, even commercially.
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Table
| protein | MolecularPathways |
|---|---|
| HIST1H2BA | Oxidative stress |
| MDH2 | Oxidative stress |
| TGM4 | Oxidative stress |
| GPX4 | Oxidative stress |
| GLUL | Oxidative stress |
| HSP90B1 | Oxidative stress |
| HSPA5 | Oxidative stress |
| ACE | Oxidative stress |
| HSPA2 | Oxidative stress |
| RPS27A | Oxidative stress |
| MAP3K3 | Oxidative stress |
| APP | Oxidative stress |
| PRDX1 | Oxidative stress |
| AKAP4 | Oxidative stress |
| PKAR1A | Energy and metabolism and Mitochondrial dysfunction |
| AK7 | Energy and metabolism and Mitochondrial dysfunction |
| CCT6B | Energy and metabolism and Mitochondrial dysfunction |
| HSPA2 | Energy and metabolism and Mitochondrial dysfunction |
| ODF2 | Energy and metabolism and Mitochondrial dysfunction |
| DLD | Energy and metabolism and Mitochondrial dysfunction |
| ATP5D | Energy and metabolism and Mitochondrial dysfunction |
| NDUFS1 | Energy and metabolism and Mitochondrial dysfunction |
| UQCRC2 | Energy and metabolism and Mitochondrial dysfunction |
| COX5B | Energy and metabolism and Mitochondrial dysfunction |
| PDH | Energy and metabolism and Mitochondrial dysfunction |
| PHGPx | Energy and metabolism and Mitochondrial dysfunction |
| VDAC | Energy and metabolism and Mitochondrial dysfunction |
| COX6B | Energy and metabolism and Mitochondrial dysfunction |
| AKAP4 | Energy and metabolism and Mitochondrial dysfunction |
| ACTB | Cytoskeleton integrity |
| KRT1 | Cytoskeleton integrity |
| ODF2 | Cytoskeleton integrity |
| TEK1 | Cytoskeleton integrity |
| TEK4 | Cytoskeleton integrity |
| TEK5 | Cytoskeleton integrity |
| TUBB2B | Cytoskeleton integrity |
| ACTB | Cytoskeleton integrity |
| HSPA2 | Protein folding and degradation Spermatogenesis and sperm function |
| CLU | Protein folding and degradation Spermatogenesis and sperm function |
| PSMB4 | Protein folding and degradation Spermatogenesis and sperm function |
| PSMB5 | Protein folding and degradation Spermatogenesis and sperm function |
| PSMB6 | Protein folding and degradation Spermatogenesis and sperm function |
| PSMA3 | Protein folding and degradation Spermatogenesis and sperm function |
| Importin | Protein folding and degradation Spermatogenesis and sperm function |
| Exportin | Protein folding and degradation Spermatogenesis and sperm function |
| HSP 70 | Protein folding and degradation Spermatogenesis and sperm function |
| AKAPs | Protein folding and degradation Spermatogenesis and sperm function |
| HSPA2 | Protein folding and degradation Spermatogenesis and sperm function |
| CRISPLD2 | Sperm DNA damage |
| CRISPLD2 | Sperm DNA damage |
| RARRES1 | Sperm DNA damage |