Table 4: Allelic Association of 38 SNPs in ART3 with NOA in Japanese Population (442 NOA Patients versus 475 Controls)

OKADA, Hiroyuki, et al. Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility. PLoS genetics, 2008, 4. Jg., Nr. 2, S. e26.

Publication: https://doi.org/10.1371/journal.pgen.0040026

Description

SNPs ART3-14, ART3-17, ART3-25 and ART3-32 show statistical significance and are subjected to haplotype analysis as shown in Figure 6.
Abbreviations:(a): Nucleotide position from the first nucleotide of exon 1.(b):Permutation p-values generated by 10,000 iterations. SNPs in bold show statistical significance based on the permutation p-values.

Disclaimer

The publication Genome-Wide Expression of Azoospermia Testes Demonstrates a Specific Profile and Implicates ART3 in Genetic Susceptibility by Hiroyuki Okada and Atsushi Tajima and Kazuyoshi Shichiri and Atsushi Tanaka and Kenichi Tanaka and Ituro Inoue is published under an open access no derivatives license: : https://creativecommons.org/. Open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Curation by the MFGA team

Pie chart of selected column

Table

ARTIFACTID	Number	Localization	Variation	MafCase	MafControl	SequencePosition(a)	Chi²	Nominal_P	Permutation_P(b)
rs13111494	ART3-1	5‘-upstream	T/C	37.7%	43.4%	-10376	3.96	0.047	0.36
rs9995300	ART3-2	5‘-upstream	A/G	38.7%	35.8%	-2520	1.66	0.20	0.81
rs4859609	ART3-3	intron2	A/G	39.3%	43.2%	3333	2.84	0.092	0.55
rs7666159	ART3-4	intron2	T/C	51.5%	48.7%	3941	1.4	0.24	0.87
rs4859611	ART3-5	intron2	T/C	43.9%	48.8%	5562	4.42	0.035	0.29
rs10007524	ART3-6	intron2	G/A	34.6%	30.7%	7070	3.14	0.077	0.49
rs4859612	ART3-7	intron3	T/G	16.8%	17.8%	9950	0.29	0.59	1
rs17001357	ART3-8	intron3	C/T	40.6%	45.9%	12048	5.13	0.024	0.22
rs4308383	ART3-9	intron3	C/T	35.8%	31.2%	12986	4.24	0.040	0.32
rs17001364	ART3-10	intron3	T/C	36.4%	31.2%	13478	5.47	0.019	0.19
rs7675618	ART3-11	intron3	G/A	35.0%	30.3%	15549	4.33	0.038	0.31
rs4859422	ART3-12	intron3	G/A	23.2%	25.1%	16736	0.88	0.35	0.96
rs4859614	ART3-13	intron3	G/A	32.8%	31.2%	17327	0.51	0.48	1
rs11097230	ART3-14	intron3	A/G	32.5%	39.3%	19801	8.73	0.0031	0.040
rs6829592	ART3-15	intron4	G/A	43.3%	46.0%	23717	1.32	0.25	0.89
rs13131187	ART3-16	intron5	A/G	42.3%	45.1%	25213	1.46	0.23	0.86
rs17001385	ART3-17	intron8	C/G	32.5%	39.2%	26422	8.84	0.0030	0.038
rs12331871	ART3-18	intron8	T/G	39.7%	43.5%	27635	2.57	0.11	0.61
rs17001390	ART3-19	intron8	C/T	34.3%	30.2%	28316	3.49	0.062	0.43
rs12510869	ART3-20	intron8	A/G	23.2%	24.4%	28670	0.36	0.55	1
rs13130116	ART3-21	intron10	C/T	22.6%	24.9%	29976	1.28	0.26	0.90
rs9307076	ART3-22	intron10	G/A	40.3%	43.5%	31256	1.92	0.17	0.75
rs4599438	ART3-23	intron10	A/G	37.5%	31.7%	32278	6.71	0.010	0.11
rs17001409	ART3-24	intron11	T/C	23.8%	25.1%	33549	0.39	0.53	1
rs6836703	ART3-25	intron11	G/A	41.2%	34.3%	34283	9.16	0.0025	0.034
rs4241584	ART3-26	intron11	C/T	30.3%	29.5%	35127	0.13	0.72	1
rs4859423	ART3-27	intron11	T/C	23.7%	25.3%	35158	0.67	0.41	0.99
rs4241586	ART3-28	intron11	T/C	39.7%	44.5%	35506	4.14	0.042	0.33
rs17001416	ART3-29	intron11	G/T	21.6%	22.5%	35935	0.20	0.66	1
rs1128864	ART3-30	exon12-nonsynonymous	T/C	38.2%	33.8%	37726	3.72	0.054	0.39
New	ART3-31	exon12-3‘-UTR	G/A	34.1%	29.4%	37857	4.58	0.032	0.28
rs14773	ART3-32	exon12-3‘-UTR	A/C	45.0%	38.1%	37861	8.96	0.0028	0.036
rs7689378	ART3-33	3‘downstream	A/G	21.7%	23.4%	38491	0.67	0.41	0.99
rs13141802	ART3-34	3‘downstream	G/C	22.3%	24.2%	38730	0.86	0.35	0.97
rs10654	ART3-35	3‘downstream	T/A	34.8%	30.5%	40031	3.64	0.056	0.41
rs7675107	ART3-36	3‘downstream	A/G	33.6%	29.1%	41918	4.19	0.041	0.32
rs6840007	ART3-37	3‘downstream	A/T	34.3%	29.7%	43329	4.42	0.036	0.30
rs4538520	ART3-38	3‘downstream	C/T	33.1%	31.7%	49092	0.39	0.53	1