Table 1 Main andrological parameters across age groups
LAURENTINO, Sandra, et al. A germ cell‐specific ageing pattern in otherwise healthy men. Aging cell, 2020, 19. Jg., Nr. 10, S. e13242.
Publication: https://doi.org/10.1111/acel.13242
Description
Normal ranges are indicated for each parameter. Results are shown as mean (SD) for each age group and Spearmans rank correlations with age as ρ (p‐value).
Disclaimer
The publication A germ cell‐specific ageing pattern in otherwise healthy men by Sandra Laurentino, Jann‐Frederik Cremers, Bernhard Horsthemke, Frank Tüttelmann, Karen Czeloth, Michael Zitzmann, Eva Pohl, Sven Rahmann, Christopher Schröder, Sven Berres, Klaus Redmann, Claudia Krallmann, Stefan Schlatt, Sabine Kliesch, Jörg Gromoll is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Share — copy and redistribute the material in any medium or format. Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Curation by the MFGA team
Pie chart of selected column
Table
| Pararmeters | Group_1N = 3418–25 years | Group_2N = 3626–35 years | Group_3N = 283645 years | Group_4N = 3946–55 years | Group_5N = 3656–65 years | Group_6N = 24>66 years | CorrelationWithAge |
|---|---|---|---|---|---|---|---|
| Testicular volume (>15 cm3) | 43.2 (13.4) | 41.5 (13.8) | 42.3 (15.7) | 39.1 (12.5) | 42.7 (12.9) | 39.6 (13.4) | −0.05 (0.51) |
| Ejaculate volume (≥1.5 ml) | 4.2 (1.7) | 4.6 (2.3) | 3.7 (1.8) | 3.2 (1.5) | 2.9 (1.5) | 2.0 (1.2) | −0.41 (3.86 × 10^−9 |
| Sperm concentration (≥15 million/ml) | 39.5 (37.3) | 47.6 (37.8) | 34.5 (30.7) | 53.5 (45.1) | 52.7 (50.1) | 62.9 (43.8) | 0.08 (0.29) |
| Total sperm count (≥39 million) | 142.3 (116.2) | 206.5 (179.5) | 118.7 (86.0) | 165.4 (160.3) | 139.1 (140.5) | 122.3 (120.8) | −0.14 (0.06) |
| Progressive motility (≥32%) | 55.2 (15.1) | 57.9 (12.5) | 47.8 (16.4) | 49.8 (16.2) | 43.4 (18.7) | 35.6 (21.1) | −0.39 (1.68 × 10^−8) |
| Normal morphology (≥4%) | 4.9 (1.7) | 4.7 (1.8) | 4.6 (2.0) | 5.2 (2.1) | 4.4 (2.2) | 5.1 (2.1) | 0.01 (0.85) |
| pH (≥7.2) | 8.1 (0.3) | 8.1 (0.3) | 8.3 (0.3) | 8.2 (0.3) | 8.4 (0.5) | 8.2 (0.3) | 0.19 (0.009) |
| Vitality (>58%) | 71.2 (11.5) | 70.5 (11.4) | 66.0 (14.2) | 69.3 (11.4) | 60.6 (15.8) | 59.3 (15.9) | −0.31 (1.99 × 10^−5) |
| FSH (2–10 U/l) | 3.0 (1.9) | 3.4 (1.5) | 4.0 (2.0) | 4.1 (2.4) | 5.2 (5.9) | 6.1 (3.0) | 0.36 (2.08 × 10−7) |
| LH (1–7 U/l) | 3.0 (0.9) | 3.2 (1.1) | 3.5 (1.5) | 3.0 (1.1) | 2.8 (1.2) | 4.0 (1.7) | 0.02 (0.81) |
| Total testosterone (>12 nmol/l) | 23.9 (7.3) | 23.8 (6.7) | 21.2 (6.8) | 19.4 (6.2) | 20.8 (6.2) | 24.1 (9.3) | −0.12 (0.09) |
| SHBG (11–71 nmol/l) | 38.2 (12.8) | 36.6 (12.8) | 37.2 (11.9) | 39.7 (13.1) | 47.3 (17.7) | 58.8 (19.3) | 0.32 (3.56 × 10^−6) |
| Free testosterone (>250 pmol/l) | 494.4 (128.5) | 501.5 (103.8) | 435.8 (138.7) | 369.0 (111.3) | 361.2 (84.9) | 361.3 (117.4) | −0.47 (6.89 × 10^−12) |
| DHT (0.5–2.0 nmol/l) | 0.9 (0.2) | 0.8 (0.2) | 0.8 (0.2) | 0.8 (0.3) | 0.8 (0.3) | 1.0 (0.4) | −0.004 (0.95) |
| Oestradiol (<250 pmol/l) | 89.0 (31.3) | 86.8 (26.9) | 85.6 (34.8) | 78.1 (28.8) | 88.5 (32.2) | 98.1 (33.4746) | 0.01 (0.87) |
| Prolactin (<500 mU/l) | 297.0 (165.0) | 303.0 (204.4) | 225.5 (97.2) | 189.4 (118.2) | 165.3 (92.6) | 199.4 (56.9) | −0.38 (3.43 × 101−8) |
| Prostate‐specific antigen (<4 µg/l) | 0.5 (0.2) | 0.6 (0.3) | 0.7 (0.5) | 0.9 (0.8) | 1.5 (1.3) | 1.9 (1.7) | 0.45 (2.70 × 10^-11) |