A genomics approach to male infertility
Naif Alhathal, Sateesh Maddirevula, Serdar Coskun, Hamed Alali, Mirna Assoum, Thomas Morris, Hesham A. Deek, Soha A. Hamed, Shaheed Alsuhaibani, Abdulmalik Mirdawi, Nour Ewida, Mashael Al-Qahtani, Niema Ibrahim, Firdous Abdulwahab, Waleed Altaweel, Majed J. Dasouki, Abdullah Assiri, Wafa Qabbaj & Fowzan S. Alkuraya, 28.07.2020
ALHATHAL, Naif, et al. A genomics approach to male infertility. Genetics in Medicine, 2020, S. 1-9.
Publication: https://doi.org/10.1038/s41436-020-0916-0
Disclaimer
The publication A genomics approach to male infertility by Naif Alhathal, Sateesh Maddirevula, Serdar Coskun, Hamed Alali, Mirna Assoum, Thomas Morris, Hesham A. Deek, Soha A. Hamed, Shaheed Alsuhaibani, Abdulmalik Mirdawi, Nour Ewida, Mashael Al-Qahtani, Niema Ibrahim, Firdous Abdulwahab, Waleed Altaweel, Majed J. Dasouki, Abdullah Assiri, Wafa Qabbaj & Fowzan S. Alkuraya is not published under an open access license.
Therefore, only content curated by the MFGA team can be shown.
For abstract, images and tables please follow the link to the original publication.
Curation by the MFGA team
Relevant data sets presented in the publication have been identified. If possible, annotations (title, general information,
conditions, processed tissue types and processed cell types) have been added based on information from the publication.
Data set 1: Chromosomal aberrations in male infertility
Genome: Other
Conditions
| Human phenotype ontology |
Participants |
Comment |
| HP:0000789: Infertility |
30 |
|
Tissue Types
| BRENDA tissue ontology |
Maturity |
Description |
Species |
Replicates |
| BTO_0001363: testis |
|
via testicular biopsies |
|
|
Cell Types
| Cell ontology |
Maturity |
Description |
Species |
Replicates |
Cells per replicate |
| CL_0000019: sperm |
|
|
|
|
|
Data set 2: The landscape of point variants in male infertility
Genome: Whole Exome Sequencing
Conditions
| Human phenotype ontology |
Participants |
Comment |
| HP:0003251: Male infertility |
285 |
Found to have nonobstructive azoospermia or severe oligospermia (less than 1 million sperm/ml). |
| HP:control |
285 |
Ethnically matched fertile adult men who were exome sequenced as part of a trio ES approach on children with suspected Mendelian disorders and healthy parents |
