Table 1. Effect on the suscepitibility to Sertoli cell-only (SCO) phenotype of the residues at position 13 of the HLA-DRß1 molecule
Cerván-Martín M, Tüttelmann F, Lopes AM, Bossini-Castillo L, Rivera-Egea R, Garrido N, Lujan S, Romeu G, Santos-Ribeiro S, Castilla JA, Carmen Gonzalvo M, Clavero A, Maldonado V, Vicente FJ, González-Muñoz S, Guzmán-Jiménez A, Burgos M, Jiménez R, Pacheco A, González C, Gómez S, Amorós D, Aguilar J, Quintana F, Calhaz-Jorge C, Aguiar A, Nunes J, Sousa S, Pereira I, Pinto MG, Correia S, Sánchez-Curbelo J, López-Rodrigo O, Martín J, Pereira-Caetano I, Marques PI, Carvalho F, Barros A, Gromoll J, Bassas L, Seixas S, Gonçalves J, Larriba S, Kliesch S, Palomino-Morales RJ, Carmona FD. Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility. Commun Biol. 2022 Nov 10;5(1):1220. doi: 10.1038/s42003-022-04192-0. PMID: 36357561; PMCID: PMC9649734.
Publication: https://www.nature.com/articles/s42003-022-04192-0
Description
The results of the combined analysis by logistic regression and the classical MHC alleles in our dataset that contain those amino acids are shown. OR odds ratio for the reference residue, CI confidence interval.
Disclaimer
The publication Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility by Cerván-Martín M, Tüttelmann F, Lopes AM, Bossini-Castillo L, Rivera-Egea R, Garrido N, Lujan S, Romeu G, Santos-Ribeiro S, Castilla JA, Carmen Gonzalvo M, Clavero A, Maldonado V, Vicente FJ, González-Muñoz S, Guzmán-Jiménez A, Burgos M, Jiménez R, Pacheco A, González C, Gómez S, Amorós D, Aguilar J, Quintana F, Calhaz-Jorge C, Aguiar A, Nunes J, Sousa S, Pereira I, Pinto MG, Correia S, Sánchez-Curbelo J, López-Rodrigo O, Martín J, Pereira-Caetano I, Marques PI, Carvalho F, Barros A, Gromoll J, Bassas L, Seixas S, Gonçalves J, Larriba S, Kliesch S, Palomino-Morales RJ, Carmona FD. is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Curation by the MFGA team
Pie chart of selected column
Table
ARTIFACTID | SCO Frequency | Control Frequency | P | OR |
---|---|---|---|---|
Ser | 51.40 | 37.75 | 1.32E-08 | 1.80 |
Arg | 8.65 | 14.07 | 7.93E-04 | 0.55 |
Tyr | 11.45 | 15.43 | 3.86E-02 | 0.72 |
Gly | 3.51 | 5.36 | 9.71E-02 | 0.63 |
Phe | 11.21 | 13.40 | 1.96E-01 | 0.81 |
His | 13.79 | 13.99 | 7.26E-01 | 0.95 |