Male Fertility Gene Atlas

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Table 1: Parameters of the patient samples included

LAURENTINO, Sandra, et al. High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting. Clinical epigenetics, 2019, 11. Jg., Nr. 1, S. 127.

Publication: https://doi.org/10.1186/s13148-019-0720-3

Description

Mean values of the testicular volumes per patient group are given as well as the percentage of tubules showing the most advanced stage of germ cell differentiation. Finally, it is indicated whether mTESE samples contained sperm KS Klinefelter syndrome, + with testicular germ cells, − without testicular germ cells, mTESE microsurgical testicular sperm extraction, Normal testicular tissues with qualitatively normal spermatogenesis, SCO Sertoli cell-only syndrome, SPC spermatocyte, SPG spermatogonia, SPT spermatid, TS tubular shadows.

Disclaimer

The publication High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting by Sandra Laurentino, Laura Heckmann, Sara Di Persio, Xiaolin Li, Gerd Meyer zu Hörste, Joachim Wistuba, Jann-Frederik Cremers, Jörg Gromoll, Sabine Kliesch, Stefan Schlatt and Nina Neuhaus is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Permits to share, copy and redistribute the material in any medium or format and to adapt, remix, transform, and build upon the material for any purpose, even commercially.

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Table

Patients Karyotype TotalTestisVolume(ml) %spt %spc %spg %sco %ts Sperm(mtese)
Normal (n=5) Not determined 20.7(+/- 11.2) 66.0 (+/- 13.4) 22.2 (+/- 8.9) 1.6 (+/- 1.4) 0.2 (+/- 0.4) 1.4 (+/- 1.0) Yes
SCO (n=3) 46;XY 8.7 (+/- 3.8) 0 0 0 99.0 (+/- 1.0) 1 (+/- 1.0) No
KS+ (n=4) 1:48;XXYY & 2-4:47;XXY 7.8 (+/- 5.7) 0.3 (0.5) 1.75 (+/- 2.9) 0 73.3 (+/- 25.6) 24.3 (+/- 26.9) 1: yes & 2-4: no
KS- (n=3) 1-3:47;XXY 2.0 (+/- 0) 0 0 0 19.3 (+/- 11.2) 80.7 (+/- 11.2) 1: no & 2-3: yes