Table 1: Singleton sequence variants in TEX11 found in infertile patients and controls
YANG, Fang, et al. TEX11 is mutated in infertile men with azoospermia and regulates genome‐wide recombination rates in mouse. EMBO molecular medicine, 2015, 7. Jg., Nr. 9, S. 1198-1210.
Publication: https://doi.org/10.15252/emmm.201404967
Description
Disclaimer
The publication TEX11 is mutated in infertile men with azoospermia and regulates genome‐wide recombination rates in mouse by Fang Yang, Sherman Silber, N Adrian Leu, Robert D Oates, Janet D Marszalek, Helen Skaletsky, Laura G Brown, Steve Rozen, David C Page, P Jeremy Wang is published under an open access license: https://creativecommons.org/licenses/by/4.0/. Granted rights: share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material.
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Table
| Position | NucleotideChange | ResultantChange | Patient_id | InfertileMales_azoospermic | ControlMales_fertile | ControlMales_nihDiversity_ |
|---|---|---|---|---|---|---|
| Exon 6 | 349T->A | Missense mutation_W117R | WHT3150 | 1 | ||
| Exon 6 | 405C->T | Silent mutation | WHT3171 | 1 | ||
| Exon 7 | 424G->A | Missense mutation_V1421 | WHT3417 | 1 | ||
| Exon 7 | 515A->G | Missense mutation_Q172R | WHT3500 | 1 | ||
| Exon 10 | 731C->T | Missense mutation_T2441 | WHT2546 | 1 | ||
| Exon 16 | 1258Ins (TT) | Frameshift mutation_1258GATG->TTGGTA | WHT3759 | 1 | ||
| Exon 26 | 2243T->C | Missense mutation_V748A | WHT2499 | 1 | ||
| Exon 27 | 2319T->C | Silent mutation | WHT2546 | 1 | ||
| Intron 3 | -17T->C | Intronic alteration | WHT3448 | 1 | ||
| Intron 5 | -48G>A | Intronic alteration | WHT3040 | 1 | ||
| Intron 10 | +42C->A | Intronic alteration | WHT3839 | 1 | ||
| Intron 12 | -28T->C | Intronic alteration | WHT3058 | 1 | ||
| Intron 15 | -64G->A | Intronic alteration | WHT3158 | 1 | ||
| Intron 21 | -1G->A | Alteration of splicing acceptor site | WHT2445 | 1 | ||
| Intron 22 | -37A->G | Intronic alteration | WHT3059 | 1 | ||
| Intron 24 | +119->A | Intronic alteration | WHT3158 | 1 | ||
| Intron 27 | -55A->C | Intronic alteration | WHT2546 | 1 | ||
| Intron 28 | -44A->G | Intronic alteration | WHT3864 | 1 | ||
| Exon 7 | 466A->G | Missense mutation_M152V | 1 | |||
| Intron 20 | +16A->G | Intronic alteration | 1 | |||
| Intron 23 | -44C->T | Intronic alteration | 1 |